Inframammary Dermatitis: A Case of Localized Late-Onset Darier's Disease
نویسندگان
چکیده
Darier's disease (DD) is an autosomal dominant inherited genodermatosis which is often under- or misdiagnosed. In the majority of cases, the disease manifests in adolescents or young adults with small brownish-yellow, warty, hyperkeratotic papules in multiple seborrheic areas of the body. Localized DD (LDD) is a clinical variant, first described by Kreibich in 1906; only a few cases are reported in the literature. We described the case of an aged woman presenting with LDD, and we review the literature on this subject.
منابع مشابه
Localized Darier's disease or Acantholytic Dyskeratotic epidermal nevus: A case report
Patients with keratotic lesions distributed in a unilateral, linear, zosteriform or localized pattern and revealing histopathologic features of dyskeratotic acantholysis have been reported previously. There is some controversy in the appropriate nosologic classification of this entity. Some authors consider it as a localized form of Darier’s disease while others place it as a variant of e...
متن کاملEfficacy of the Radiotherapy on Darier's Disease: An Indirect Evidence
Darier's disease (DD) is an autosomal dominant dermatosis characterized by hyperkeratotic papules that are mainly located in the seborrheic areas and pushups, handheld wells, and nails. The disease often appears at a young age, typically by the third decade, with no sex predilection. There is currently no standard therapy and there are usually topical palliative therapies. We present the case o...
متن کاملBullous Darier’s disease mimicking Hailey-Hailey disease
BACKGROUND The bullous variant of Darier's disease (DD) is a rare type characterized by histological and clinical overlap with Hailey-Hailey disease (HDD). CASE REPORTS The following case report describes two cases of familial DD; a 51-year-old woman who presented with erythematous plaques, covered by small blisters in axillary and inguinal areas, and the first patient's daughter, who present...
متن کاملDarier's disease following radiotherapy for carcinoma of cervix.
Darier-White disease is due to a defect in the ATP2A2 gene encoding the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA2b). We report a case of carcinoma cervix in whom Darier's disease manifested after the initiation of radiation therapy. Conventional cytogenetics on peripheral blood revealed non-clonal constitutional autosomal and X chromosome abnormalities suggesting radiation induced ...
متن کاملA localized form of Darier's disease.
We report the case of a 33-year-old woman who presented with skin manifestations that resulted in a differential diagnosis of either an epidermal nevus or a localized form of Darier's disease. We discuss the arguments for and against each possibility. The available data on localized forms of Darier's disease are also discussed.
متن کامل